Dr Barbara Philips became a Reader in Intensive Care Medicine in June 2014. She has been a clinical academic at St George’s, University of London since 1999.
She trained in Intensive Care Medicine and Anaesthesia in Scotland and was based at the Royal Infirmary, Edinburgh. This included 18 months as a Clinical Research Fellow with the Scottish Transplantation Service, during which she obtained her MD (University of London). Dr Philips was the first woman candidate to gain the UK Diploma in Intensive Care Medicine. She qualified in Medicine from King’s College Hospital, London and gained a First Class Honours intercalated degree in Nutrition with Basic Medical Sciences.
Dr Philips's research is clinical and translational and is based in the General Intensive Care Unit at St George’s Hospital. Her research takes a particular interest in acute kidney injury, pharmacokinetics in critically ill patients, organ cross talk and metabolic disorders.
Dr Philips is involved in writing national guidelines for the peri-operative care of patients undergoing adrenalectomy for the British Association of Endocrine and Thyroid Surgeons (BAETS) on behalf of the Royal College of Anaesthetists.
She is the lead for the final year of the Medicine MBBS courses and also the Lead for final year OSCE exams at St George's.
Dr Philips is an elected council member of the Intensive Care Society (ICS), a member of the Intensive Care Foundation (ICF) for research, and Chair of the ICS Education and Training Committee. She is Chair of the local Specialty Group for Critical Care within the London South research network and is a board member of the London Acute Kidney Injury (AKI) Network. She also sits on the advisory editorial boards for the British Journal of Anaesthesia and for Critical Care.
Dr Philips is a reviewer for National Institute for Health Research (NIHR) grant applications and an examiner for the Faculty of Intensive Care Medicine (FICM).
She has an interest in clinical ethics and is the Deputy Chair of the Clinical Ethics Committee at St George's.
Dr Philips is the lead for the final year of the Medicine MBBS and for final year exams at St George's. She organises the Critical Care attachment for final year students and offers student-selected components and elective opportunities for final year students. She is also a personal tutor.
Dr Philips offers projects to second year biomedical students as well as BSc projects to final year biomedical students and MBBS students doing intercalated degrees. She runs small group seminars to final year students and lectures first year students on the four year Medicine MBBS. She teaches during clinical work both in intensive care and in theatres. She also chairs the Exceptional Circumstances Committee.
In postgraduate teaching, Dr Philips supervises four PhD students and is the educational supervisor for three advanced International Continence Society trainees. She is an examiner for the Faculty of Intensive Care Medicine (FICM) and a member of the Multiple Choice Questions and Single Best Answer writing committees.
She is Chair of the International Continence Society Education Committee and a co-opted member of the Education Committee of the Royal College of Anaesthetists, representing Intensive Care Medicine.
- Lane K, Dixon JJ, McKeown D, Johnston A, van Schaik RH, van Fessem M, MacPhee IA, Philips BJ. Using tramadol to measure CYP2D6 metabolism in critically ill adults. Intensive Care Med. 2014 Aug;40:1177-8.
- Philips BJ, Lane K, Dixon J, Macphee I. The effects of acute renal failure on drug metabolism. Expert Opin Drug Metab Toxicol 2014; 10: 11-23
- Memoli G, Dawson D, Simmons D, Barham R, Grounds M, Hamilton M, Philips B. Towards the acoustical characterisation of an Intensive Care Unit. Applied Acoustics 2014; in press
- Lane K, Dixon JJ, MacPhee IA, Philips BJ. Renohepatic crosstalk: does acute kidney injury cause liver dysfunction? Nephrol Dial Transplant 2013; 28: 1634-47
- Kirwan CJ, Philips BJ, Macphee IA. Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. Critical care research and practice 2013; 2013: 406075
- Kirwan CJ, MacPhee IA, Lee T, Holt DW, Philips BJ. Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients. Intensive Care Med 2012; 38: 76-84
Dr Iain MacPhee (Reader in Renal Medicine, St George's University of London)
Professor Emma Baker (Clinical Pharmacology, St George's University of London)
Professor Mike Sharland (Paediatric infectious diseases, St George's University of London)
Professor Sanjeev Krishna (Infectious Diseases, St George's University of London)
Professor Atholl Johnson (Pharmacology, Barts and St George's University of London)
Dr Tim Planche (Medical Microbiology, St George's University of London)
Dr Andrew Rhodes (Critical Care, St George's Hospital)
Dr Maurizio Cecconi (Critical Care, St George's Hospital)
Dr Mark Dockrell (Lead Scientist, Southwest Thames Renal Research Institute)
Professor R van Shaik (Clinical Chemistry, Erasmus University, Netherlands)
Dr Joe Standing (Senior Research Associate ICH Infection, Immunity, Inflammation and Physio Med, UCL)
Dr Marlies Ostermann (Intensive Care Medicine and Nephrology, Guys and St Thomas’ Hospital)
Dr Chris Kirwan (Intensive Care Medicine and Nephrology, Royal London Hospital)
Dr David Brealey (Intensive Care Medicine, UCL)
Dr Phil Hopkins (Intensive Care Medicine, King’s College Hospital)
Dr Richard Barham (Acoustics, National Physical Laboratory)
Dr Gianluca Memoli (Acoustics, National Physical Laboratory)
Dr Philips's research interests are in acute kidney injury (AKI), critical illness and sepsis, with particular emphasis on the impact of critical illness and AKI on the pharmacokinetics of drugs.
Her most recent area of research development is a collaboration with Professor Mike Sharland (Professor of Paediatric Infectious Diseases), working with Dr Joe Standing at UCL to use population pharmacokinetics to investigate the impact of critical illness on antibiotic concentrations. Dr Philips is supervising a PhD student on this project.
Dr Philips is also collaborating with Dr David Brealey of UCL to set up a trial testing the use of a new technology (Cytosorb®) in the treatment of sepsis. Her research aims to determine the impact of the system on antibiotic concentrations in vivo.
Dr Philips has a developed a novel method of measuring renal function in AKI for in vivo research. Her work has shown that AKI has a direct impact on the metabolic function of the liver, in particular the Cytochrome P450 enzymes. Both clinical studies and cell based research are currently being conducted in this area.
Dr Philips has also developed collaborations with the National Physical Laboratory. They have developed technology for soundscaping areas and Dr Philips's work is using this to describe in detail the noise that patients experience in intensive care, both in terms of strength and quality. She is working on methods of relating this to patient experience with the aim of improving the environment for patients and visiting relatives in the future.