MSc Clinical Genomics consists of 8 modules and a research project which will equip you with the necessary skills and knowledge to advance your understanding in the interpretation and clinical application of genomic data.

human gene

Core Modules 

Understanding genetic technologies

This module will equip you with the knowledge and applicability of the principles behind commonly used molecular techniques. You will learn how to evaluate which laboratory investigations are most suitable for a given clinical scenario and critically review the processes used in issuing a laboratory report from sample checking to issuing of a diagnostic report. You will also learn how to design a panel of genes for analysis using next generation sequencing technologies applicable to a specific clinical phenotype.

Delivered at St George's

Clinical Interpretation of genomic data

You will learn how to analyse the key features of a genetic variant which affect the prior likelihood of pathogenicity. You will understand how to critically examine the clinical context within which a genetic variant will be interpreted. This module will teach you how to apply in silico variant analysis tools to evaluate genetic variants, equipping you with the skills to critically evaluate the report generated by in silico variant analysis tools. By the end of the module you will be able to demonstrate the interrogation of population level genomic databases with respect to a specific genetic variant alongside the interrogation of mutation databases with respect to a specific genetic variant.

Delivered at St George's

Communication of genetic information and ethics

This module will teach you how to communicate complex genetic data and complex information about variants of unknown significance effectively to patients/families effectively and sensitively. It will allow you to critically evaluate the ethical issues surrounding consent for genetic testing with an understanding and explanation of incidental findings. You will evaluate the ethical considerations of genetic testing and be able to formulate cogent arguments for and against testing in specific clinical scenarios.

Delivered at St George's

Personal and professional development portfolio

You will assemble a portfolio that demonstrates learning and progression in the application of genetic technologies, the interpretation of genomic data and the communication of complex genetic information to patients. In this module you will demonstrate application of the approaches undertaken in the clinical interpretation of genomic data. You will also critically appraise the medical literature relevant to the interpretation of genetic data. Alongside this you will reflect on the effect of genetic test results on the patient and other healthcare professionals and on your communication skills when imparting complex genetic information to patients/families and directed literature. You will finally propose and justify your approaches to continuing professional development.

Delivered at St George's

Research Project

The research project is studied as part of the Postgraduate Diploma or Masters in Clinical Genomics. You will select an area of interest, develop a research question and identify an appropriate method to answer that question, undertake a research project and present your findings. You will be allocated a supervisor for your project who will contribute background knowledge on your subject and methodological expertise to support you throughout the module.

Optional Modules (choose 4)

Omics techniques and their application to genomic medicine

This module covers the range of multi-omics technologies, their interpretation and application in key areas of healthcare such as cancer, rare inherited diseases and infectious diseases, as well as research.

Delivered at King's college London

Genomics in cancer pathology

This module provides detailed knowledge and understanding of the molecular mechanisms involved in cancer development, including how interrogation of a person’s own genome and the genome of tumour cells can facilitate the diagnosis and treatment of cancer.

Delivered at King's College London

Application of genomics in infectious disease

This module shows how genomics can be used to provide more accurate diagnosis, predict which drugs are likely to be more effective, and monitor treatment and control of infectious disease in both individuals and populations.

Delivered at St George's

Pharmacogenomics and stratified healthcare

This module provides a comprehensive overview of the analytical strategies and techniques used in pharmacogenomics and explores some of the challenges and limitations in this field. It also provides an overview of the different type of genomic biomarkers currently in use or emerging.

Delivered at King's College London

Bioinformatics, interpretation and data quality in genome analysis

This module provides the knowledge and understanding required to critically interpret existing genomic research, and develop the skills to formulate research questions. It also provides the skills to collect, analyse and interpret NHS data using a basic range of statistical and bioinformatics techniques.

Delivered at King's College London

Ethical, legal and social perspectives on genomic medicine

This module aims to provide a framework for ethical understanding of medical genomics. Students will be provided with a platform of ethical understanding from which to consider issues of human confidentiality, autonomy, disclosure, informed consent and natural justice. 

Delivered at St George's

Cardiovascular genetics and genomics

The aim of this module is to introduce students to the role of genomics in the pathogenesis of cardiovascular disease, both in terms of common and rare disease, and will discuss the impact our growing knowledge of the genomic aetiology of these conditions is having on management.

Delivered at St George's

Teaching and learning skills

This module addresses the key principles and practice of effective teaching, learning support and assessment in healthcare and science education, enabling you to develop your teaching skills with a scholarly and professional approach to your practice as a teacher in higher education. You will be required to apply those key principles both in a microteaching session with fellow students and in a session in a healthcare or science setting on which you will reflect and report. The module has been mapped against the UK Professional Standards Framework (UKPSF) for higher education.

Delivered at St George's


Last Updated: Wednesday, 26 October 2016 16:23