Tel: +44 (0) 208 725 5722
Email: hstaines@sgul.ac.uk
Biography
Following a BSc in Biochemistry at the University of Kent at Canterbury, I studied for a DPhil in Cellular Physiology at the University Laboratory of Physiology, Oxford. During this time and my initial postdoctoral years, I examined the transport mechanisms used by the malaria parasite, Plasmodium falciparum, to obtain nutrients and export waste products while developing within human red blood cells. During a Wellcome Trust Research Career Development Fellowship (2005–09), I studied transport mechanisms in a wider range of unicellular parasites. Now, I have developed interest point-of-care diagnostics for malaria, which also aims to diagnose drug resistance in the parasite. This has led to translation of scientific studies (some that I have been involved with myself) to patient care and has provided me with great experience in managing (with others) a complex EU project like Nanomal.
Key publications
H. M. Staines, S. Ashmore, H. Felgate, J. Moore, T. Powell and J. C. Ellory (2006). Solute transport via the new permeability pathways inPlasmodium falciparum-infected human red blood cells is not consistent with a simple single channel model. Blood, 108, 3187-3194
H. M. Staines, T. Powell, J. C. Ellory, S. Egée, F. Lapaix, G. Decherf, S. L. Y. Thomas, C. Duranton, F. Lang and S. M. Huber (2003). Modulation of whole-cell currents in Plasmodium falciparum-infected human red blood cells by holding potential and serum. J. Physiol., 552, 177-183
H. M. Staines, J. C. Ellory and K. Kirk (2001). Perturbation of the pump-leak balance for Na+ and K+ in malaria-infected erythrocytes. Am. J. Physiol., 280, C1576-C1587