Recent publications

Dalee Zhou, Zuhal Eraslan, Dawson Miller, Isobel Taylor, Jaewon You, Samuel J. Grondin, Martha Vega, Prashiela Manga, Philip S. Goff, Elena V. Sviderskaya, Steven S. Gross, Qiuying Chen, Jonathan H. Zippin. Two-pore channel 2 is required for soluble adenylyl cyclase-dependent regulation of melanosomal pH and melanin synthesis. Pigment Cell and Melanoma Research. https://doi.org/10.1111/pcmr.13177

Oanh Tran, Sara Bertelli, Holly J. Hughes, Luka Lozo, Andrew Plested, Katalin Török. Novel iGluSnFR3 variants with improved kinetics and dynamic range for tracking high frequency firing at glutamatergic synapses. bioRxiv: https://doi.org/10.1101/2024.08.30.610471

Philip S. Goff, Shyamal Patel, Tom Carter, Michael S. Marks, Elena V. Sviderskaya. Enhanced MC1R-signalling and pH modulation facilitate melanogenesis within late endosomes of BLOC-1-deficient melanocytes. bioRxiv.org - the preprint server for Biology

Constantinou SM & DC Bennett. Cell senescence and the genetics of melanoma development. Genes, Chromosomes and Cancer. (Accepted.)

Bryant D, S Barberan-Martin, R Maeshima, I del Valle Torres, M Rabii, W Baird, A Sauvadet, C Demetriou, P Jones, N Knöpfel, F Michailidis, M Riachi, DC Bennett, D Zecchin, A Pittman, S Polubothu, S Hart, VA Kinsler. RNA therapy for oncogenic NRAS-driven nevi induces apoptosis. J. Invest. Dermatol. (Online early.) https://doi.org/10.1016/j.jid.2024.04.031

Wang D, Woodcock E, Yang X, Nishikawa H, Sviderskaya EV, Oshima M, Edwards C, Zhang Y and Korchev Y. Exploration of individual colorectal cancer cell responses to H2O2 eustress using hopping probe scanning ion conductance microscopy. Science Bulletin. https://doi.org/10.1016/j.scib.2024.04.004

Lamoreux ML & DC Bennett Perspective: Scientists’ Warning on the problem with overpopulation and living systems. J. Popul. Sustainabil. (2024) 8(1), 95-111. https://doi.org/10.3197/JPS.63799953906873

Bennett, DC. Review: Are moles senescent? Pigm. Cell Melanoma Res 2024 May;37(3):391-402. https://doi.org/10.1111/pcmr.13163

Chikh A, Raimondi C. Endothelial Neuropilin-1: a multifaced signal transducer with an emerging role in inflammation and atherosclerosis beyond angiogenesis. Biochem Soc Trans. 2024 Feb 28;52(1):137-150.

Dulloo I, Tellier M, Levet C, Chikh A, Zhang B, Blaydon DC, Webb CM, Kelsell DP, Freeman M. Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway. Mol Cell. 2024 Jan 18;84(2):277-292.e9. doi: 10.1016/j.molcel.2023.12.012.

Hordijk S, Carter T, Bierings R. A new look at an old body: molecular determinants of Weibel-Palade body composition and VWF exocytosis. J Thromb Haemost. 2024: S1538-7836(24)00055-2. doi: 10.1016/j.jtha.2024.01.015. Epub ahead of print. PMID: 38307391.

Poch A, Dougherty MP, Roman RA, Chorich L, Hawkins Z, Kim SH, Kim HG, Layman LC. Prevalence of pathogenic variants and digenic disease in patients diagnosed with normosmic hypogonadotropic hypogonadism/Kallmann Syndrome. Mol Cell Endocrinol. 2024 Apr 7;589:112224. doi: 10.1016/j.mce.2024.112224

Soo JK, JT Castle & DC Bennett (2023). Preferential killing of melanoma cells by a p16-related peptide. Biol. Open, 12(8): bio059965. https://doi.org/10.1242/bio.059965

Lee J, Kim Y, Ataliotis P, Kim HG, Kim DW, Bennett DC, Brown NA, Layman LC, Kim SH. Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development. Sci Rep. 2023 Jul 29;13(1):12309. https://doi.org/10.1038/s41598-023-38017-9

Ozek G, Aksoylar S, Uçar SK, Canda E, Akcan M, Cartı O, Siviş ZO, Oymak Y, Yazıcı H, Bax B, Bulut FD, Yoldaş Çelik M, Erdem F, Çoker M, Kansoy S. Hematopoietic stem cell transplantation with reduced toxicity conditioning regimen in mitochondrial neurogastrointestinal encephalopathy syndrome. Pediatr Blood Cancer. 2023 Jul;70(7):e30334. doi: 10.1002/pbc.30334.

Cotterill S, Yamaguchi M. Role of Drosophila in Human Disease Research 3.0. Int J Mol Sci. 2023 Dec 25;25(1):292.

Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A, Raimondi C. Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow. Sci Signal. 2023 May 23;16(786):eabo4863

Garima Jain, Parimal Das, Prashant Ranjan, Neha, Ferran Valderrama and Clara Cieza-Borrella. Urinary extracellular vesicles miRNA—A new era of prostate cancer biomarkers. Front. Genet. 2023 14:1065757. https://doi:10.3389/fgene.2023.1065757

Tran, O.; Kerruth, S.; Coates, C.; Kaur, H.; Peracchia, C.; Carter, T.; Török, K. Ca2+-Dependent and-Independent Calmodulin Binding to the Cytoplasmic Loop of Gap Junction Connexins. Int. J. Mol. Sci. 2023, 24, 4153. https://doi.org/10.3390/ijms24044153

Meli, A.; McCormack, A.; Conte, I.; Chen, Q.; Streetley, J.; Rose, M.L.; Bierings, R.; Hannah, M.J.; Molloy, J.E.; Rosenthal, P.B. Carter T. Altered Storage and Function of von Willebrand Factor in Human Cardiac Microvascular Endothelial Cells Isolated from Recipient Transplant Hearts. Int. J. Mol. Sci. 2023, 24, 4553. https://doi.org/10.3390/ijms24054553

Tran, O., Hughes, H., Carter, T. & Török T. (2023) Development and characterisation of novel jGCaMP8f calcium sensor variants with improved kinetics and fluorescence response range. Frontiers in Cellular Neuroscience article collection on 'The Development and Application of Genetically Encoded Sensors for Resolving the Physiology or Pathogenesis in Various Behaviours and Diseases' (2023) 17:1155406. doi: 10.3389/fncel.2023.1155406

Maurice Swinkels, Sophie Hordijk, Petra E. Bürgisser, Johan A. Slotman, Tom Carter, Frank W.G. Leebeek, A.J. Gerard Jansen, Jan Voorberg, Ruben Bierings (2023). Quantitative super-resolution imaging of platelet degranulation reveals differential release of von Willebrand factor and von Willebrand factor propeptide from alpha-granules. Journal of Thrombosis and Haemostasis, In press https://doi.org/10.1016/j.jtha.2023.03.041

Isolation, culture, and transfection of melanocytes. Goff, PS, Castle, JT, Kohli, JS, Sviderskaya, EV, & Bennett, DC (2023). Current Protocols, 3, e774. https://doi.org/10.1002/cpz1.774

S. Yaganoglu, K. Kalyviotis, N. Helassa, C. Vagena-Pantoula, D. Jülich, B.M. Gaub, M. Welling, T. Lopes, D. Lachowski, S.S. Tang, A. Del Rio Hernandez, V. Salem, D.J. Müller, S.A. Holley, J. Vermot, J. Shi, K. Török, P. Pantazis. Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi. Nature Communications (2023) 14, 4352. doi:10.1038/s41467-023-40134-y

Testing the cognitive effects of tadalafil. Neuropsychological secondary outcomes from the PASTIS trial.Pauls MM, Fish J, Binnie LR, Benjamin P, Betteridge S, Clarke B, Dhillon MK, Ghatala R, Hainsworth FA, Howe FA, Khan U, Kruuse C, Madigan JB, Moynihan B, Patel B, Pereira AC, Rostrup E, Shtaya AB, Spilling CA, Trippier S, Williams R, Young R, Barrick TR, Isaacs JD, Hainsworth AH. Cereb Circ Cogn Behav. 2023 Sep 26;5:100187. doi: 10.1016/j.cccb.2023.100187. eCollection 2023.PMID: 37811523

PDE5 inhibitor drugs for use in dementia. Hainsworth AH, Arancio O, Elahi FM, Isaacs JD, Cheng F.Alzheimers Dement (N Y). 2023 Sep 25;9(3):e12412. doi: 10.1002/trc2.12412.

One-health approach to canine cognitive decline: Dogs Overcoming Geriatric Memory and Aging Initiative for early detection of cognitive decline.Hunter RP, Ehrenzweig J, Hainsworth A, Crawford A, Dagan A, Sage J, Araujo J.Am J Vet Res. 2023 Sep 26:1-5.

Ben-Mahmoud A, Kishikawa S, Gupta V, Leach NT, Shen Y, Moldovan O, Goel H, Hopper B, Ranguin K, Gruchy N, Maas SM, Lacassie Y, Kim SH, Kim WY, Quade BJ, Morton CC, Kim CH, Layman LC, Kim HG. A cryptic microdeletion del(12)(p11.21p11.23) within an unbalanced translocation t(7;12)(q21.13;q23.1) implicates new candidate loci for intellectual disability and Kallmann syndrome. Sci Rep. 2023 Aug 10;13(1):12984.

P-selectin mobility undergoes a sol-gel transition as it diffuses from exocytosis sites into the cell membrane. Hellen N, Mashanov GI, Conte IL, le Trionnaire S, Babich V, Knipe L, Mohammed A, Ogmen K, Martin-Almedina S, Török K, Hannah MJ, Molloy JE, Carter T. Nat Commun. (2022).13(1):3031. doi: 10.1038/s41467-022-30669-x. PMID: 35641503 

What does aducanumab treatment of Alzheimer's disease mean for research on vascular cognitive disorders? Wallin A, Alladi S, Black SE, Chen C, Greenberg SM, Gustafson D, Isaacs JD, Jokinen H, Kalaria R, Mok V, Pantoni L, Pasquier F, Roman GC, Rosenberg GA, Schmidt R, Smith EE, Hainsworth AH. Cereb Circ Cogn Behav. 2022 Feb 11;3:100044.

Test-retest reliability of arterial spin labelling for cerebral blood flow in older adults with small vessel disease. Binnie LR, Pauls MMH, Benjamin P, Dhillon MK, Betteridge S, Clarke B, Ghatala R, Hainsworth FAH, Howe FA, Khan U, Kruuse C, Madigan JB, Moynihan B, Patel B, Pereira AC, Rostrup E, Shtaya ABY, Spilling CA, Trippier S, Williams R, Isaacs JD, Barrick TR, Hainsworth AH. Transl Stroke Res. 2022 Aug;13(4):583-594. doi: 10.1007/s12975-021-00983-5. Epub 2022 Jan 26. PMID: 35080734

Vascular cognitive impairment and dementia: An early career researcher perspective. Silva NCBS, Bracko O, Nelson AR, de Oliveira FF, Robison LS, Shaaban CE, Hainsworth AH, Price BR. Alzheimers Dement (Amst). 2022 Apr 27;14(1):e12310. doi: 10.1002/dad2.12310. eCollection 2022. PMID: 35496373

The epidemiology is promising, but the trial evidence is weak. Why pharmacological dementia risk reduction trials haven't lived up to expectations, and where do we go from here? Peters R, Dodge HH, James S, Jicha GA, Meyer PF, Richards M, Smith AD, Yassine HN, Abner E, Hainsworth AH, Kehoe PG, Beckett N, Anderson CS, Anstey KJ. Alzheimers Dement. 2022 Mar;18(3):507-512. doi: 10.1002/alz.12393. Epub 2021 Nov 2. PMID: 34726352

Vasculocentric Axonal NfH in Small Vessel Disease. Anad A, Barker MK, Katanga JA, Arfanakis K, Bridges LR, Esiri MM, Isaacs JD, Prpar Mihevc S, Pereira AC, Schneider JA, Hainsworth AH. J Neuropathol Exp Neurol. 2022 Feb 24;81(3):182-192. doi: 10.1093/jnen/nlab134. PMID: 35086142

The PASTIS trial: Testing tadalafil for possible use in vascular cognitive impairment. Pauls MMH, Binnie LR, Benjamin P, Betteridge S, Clarke B, Dhillon MK, Ghatala R, Hainsworth FAH, Howe FA, Khan U, Kruuse C, Madigan JB, Moynihan B, Patel B, Pereira AC, Rostrup E, Shtaya ABY, Spilling CA, Trippier S, Williams R, Young R, Barrick TR, Isaacs JD, Hainsworth AH. Alzheimers Dement. 2022 Feb 8. doi: 10.1002/alz.12559. Online ahead of print. PMID: 35135037

Biomarkers in Rare Diseases 2.0. Bax BE. Int J Mol Sci. 2022 Apr 21;23(9):4582. doi: 10.3390/ijms23094582. PMID: 35562973

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes. Gautheron J, Lima L, Akinci B, Zammouri J, Auclair M, Ucar SK, Ozen S, Altay C, Bax BE, Nemazanyy I, Lenoir V, Prip-Buus C, Acquaviva-Bourdain C, Lascols O, Fève B, Vigouroux C, Noel E, Jéru I. BMC Med. 2022 Mar 28;20(1):95. doi: 10.1186/s12916-022-02296-2. PMID: 35341481

The role of insulators and transcription in 3D chromatin organization of flies. Chathoth KT, Mikheeva LA, Crevel G, Wolfe JC, Hunter I, Beckett-Doyle S, Cotterill S, Dai H, Harrison A, Zabet NR. Genome Res. 2022 Apr;32(4):682-698. doi: 10.1101/gr.275809.121. Epub 2022 Mar 30. PMID: 35354608.

Vascular Collagen Type-IV in Hypertension and Cerebral Small Vessel Disease. Kumar AA, Yeo N, Whittaker M, Attra P, Barrick TR, Bridges LR, Dickson DW, Esiri MM, Farris CW, Graham D, Lin WL, Meijles DN, Pereira AC, Perry G, Rosene DL, Shtaya AB, Van Agtmael T, Zamboni G, Hainsworth AH. Stroke. 2022 Dec;53(12):3696-3705.

Vesicular release probability sets the strength of individual Schaffer collateral synapses.C.D. Dürst, J.S. Wiegert, C. Schulze, N. Helassa, K. Török and T.G. Oertner. Nature Communications (2022) 13, 6126. doi.org/10.1038/s41467-022-33565-6

Kalkan Uçar S, Yazıcı H, Canda E, Er E, Bulut FD, Eraslan C, Onay H, Bax BE, Çoker M. Clinical spectrum of early onset "Mediterranean" (homozygous p.P131L mutation) mitochondrial neurogastrointestinal encephalomyopathy. JIMD Rep. 2022 Jul 10;63(5):484-493. doi: 10.1002/jmd2.12315

Mark Mencias, Michelle Levene, Kevin Blighe, Bridget E. Bax. (2021)Circulating miRNAs as Biomarkers for Mitochondrial Neuro-Gastrointestinal Encephalomyopathy. Int. J. Mol. Sci, 22(7), 3681.

Bax B (2021) Biomarkers in Rare Diseases. Int J Mol Sci. 22(2): 673. (Published online 2021 Jan 12. doi: 10.3390/ijms22020673 )

Guillaume Lapointe, Colin K. Skepper*, Lauren M. Holder, Duncan Armstrong, et al (2021) Discovery and optimization of DNA gyrase and topoisomerase IV inhibitors with potent activity against fluoroquinolone-resistant Gram-positive bacteria. Lapointe et al. J Med Chem. (in Press, published online ahead of print; doi: 10.1021/acs.jmedchem.1c00375.)

Kinyo On, Gilles Crevel, Sue Cotterill, Masanobu Itoh, Yasuko Kato (2021). Drosophila telomere capping protein HOAP interacts with DSB sensor proteins Mre11 and NbsGenes to Cells, 26 (4) pp 219-229. First published: 08 February 2021 https://doi.org/10.1111/gtc.12836

Mapping mechanical properties of living cells at nanoscale using intrinsic nanopipette-sample force interactions. Vasilii S Kolmogorov , Alexander S Erofeev, Emily Woodcock, et al. (2021), Nanoscale 13(13):6558-6568 doi: 10.1039/d0nr08349f. Epub 2021 Mar 31Sirés-Campos J, Lambertos A, Delevoye C, Raposo G, Bennett DC, Sviderskaya E, Jiménez-Cervantes C, Olivares C, García-Borrón JC (2021) Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells. Cell Mol Life Sci. 2021 Dec 18. Online ahead of print.

Atticus H. Hainsworth, Fanny M. Elahic & Roderick A. Corriveaud (2021). An introduction to therapeutic approaches to vascular cognitive impairment. Cerebral Circulation - Cognition and Behavior, 2, 100033 https://doi.org/10.1016/j.cccb.2021.100033

Peters R, Dodge HH, James S, Jicha GA, Meyer PF, Richards M, Smith AD, Yassine HN, Abner E, Hainsworth AH, Kehoe PG, Beckett N, Anderson CS, Anstey KJ. (2021). The epidemiology is promising, but the trial evidence is weak. Why pharmacological dementia risk reduction trials haven't lived up to expectations, and where do we go from here?

Alzheimers Dement. doi: 10.1002/alz.12393. Online ahead of print.Alakbarzade V, French JM, Howlett DR, Attems J, Francis PT, Stratton S, Clark CN, Pereira AC, Hainsworth AH. 2021 Cerebral amyloid angiopathy distribution in older people: A cautionary note. Alzheimers Dement (N Y). 2021 Feb 16;7(1):e12145. doi: 10.1002/trc2.12145. eCollection 2021. PMID: 33644295

Chen Q, Zhou D, Abdel-Malek Z, Zhang F, Goff PS, Sviderskaya EV, Wakamatsu K, Ito S, Gross SS, Zippin JH. (2021). Measurement of Melanin Metabolism in Live Cells by [U-13C]-L-Tyrosine Fate Tracing Using Liquid Chromatography-Mass Spectrometry. J Invest Dermatol. 141(7):1810-1818.e6. doi: 10.1016/j.jid.2021.01.007. Epub 2021 Feb 5. PMID: 33549605

Soriano I, Vazquez E, De Leon N, Bertrand S, Heitzer E, Toumazou S, Bo Z, Palles C, Pai CC, Humphrey TC, Tomlinson I, Cotterill S, Kearsey SE. (2021). Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication. PLoS Genet. 17(7):e1009526. doi: 10.1371/journal.pgen.1009526. eCollection 2021 Jul. PMID: 34228709

Kat M, Bürgisser PE, Janssen H, De Cuyper IM, Conte IL, Hume AN, Carter T, Voorberg J, Margadant C, Bierings R. (2021). GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies. Blood Adv. 5(23):5116-5127. doi: 10.1182/bloodadvances.2021004827.

Hirano M, Carelli V, De Giorgio R, Pironi L, Accarino A, Cenacchi G, D'Alessandro R, Filosto M, Martí R, Nonino F, Pinna AD, Baldin E, Bax BE, Bolletta A, Bolletta R, Boschetti E, Cescon M, D'Angelo R, Dotti MT, Giordano C, Gramegna LL, Levene M, Lodi R, Mandel H, Morelli MC, Musumeci O, Pugliese A, Scarpelli M, Siniscalchi A, Spinazzola A, Tal G, Torres-Torronteras J, Vignatelli L, Zaidman I, Zoller H, Rinaldi R, Zeviani M. (2021). Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): Position paper on diagnosis, prognosis, and treatment by the MNGIE International Network. J Inherit Metab Dis. 44(2):376-387. doi: 10.1002/jimd.12300. Epub 2020 Sep 8.

Bowman SL, Le L, Zhu Y, Harper DC, Sitaram A, Theos AC, Sviderskaya EV, Bennett DC, Raposo-Benedetti G, Owen DJ, Dennis MK, Marks MS. (2021). A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers. J Cell Biol. 220(7):e202005173. doi: 10.1083/jcb.202005173.

Elif Damla Arisan 1 , Ozge Rencuzogullari 2 , Clara Cieza-Borrella 3 , Francesc Miralles Arenas 3 , Miriam Dwek 4 , Sigrun Lange 5 , Pinar Uysal-Onganer . (2021). MiR-21 Is Required for the Epithelial-Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells.Int J Mol Sci. ;22(4):1557. doi: 10.3390/ijms22041557

Hirano, M; Carelli, V; De Giorgio, R; Pironi, L; Accarino, A; Cenacchi, G; D'Alessandro, R; Filosto, M; Martí, R; Nonino, F; et al. (Bax, BE) (2020) Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): Position Paper on Diagnosis, Prognosis and Treatment by the MNGIE International Network. Journal of Inherited Metabolic Disease. ISSN 0141-8955 https://doi.org/10.1002/jimd.12300

Bax, BE (2020) Erythrocytes as Carriers of Therapeutic Enzymes. Pharmaceutics, 12 (5). ISSN 1999-4923 https://doi.org/10.3390/pharmaceutics12050435

Kipper, K; Hecht, M; Antunes, NJ; Fairbanks, LD; Levene, M; Kalkan Uçar, S; Schaefer, A; Blakely, EL; Bax, BE (2020) Quantification of Plasma and Urine Thymidine and 2'-

Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy. J Clin Med, 9 (3). p. 788. ISSN 2077-0383 https://doi.org/10.3390/jcm9030788

Martínez-Vicente, I; Abrisqueta, M; Herraiz, C; Sirés-Campos, J; Castejón-Griñán, M; Bennett, DC; Olivares, C; García-Borrón, JC; Jiménez-Cervantes, C (2020) Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells. Cancers (Basel), 12 (10). p. 2840. ISSN 2072-6694 https://doi.org/10.3390/cancers12102840

Maurichi, A; Miceli, R; Patuzzo, R; Barretta, F; Gallino, G; Mattavelli, I; Barbieri, C; Leva, A; Cortinovis, U; Tolomio, E; et al. (2020) Analysis of Sentinel Node Biopsy and Clinicopathologic Features as Prognostic Factors in Patients With Atypical Melanocytic Tumors. J Natl Compr Canc Netw, 18 (10). pp. 1327-1336. ISSN 1540-1413 https://doi.org/10.6004/jnccn.2020.7582

Le, L; Escobar, IE; Ho, T; Lefkovith, AJ; Latteri, E; Haltaufderhyde, KD; Dennis, MK; Plowright, L; Sviderskaya, EV; Bennett, DC; et al. (2020) SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation. Mol Biol Cell. mbcE20030200. ISSN 1939-4586 https://doi.org/10.1091/mbc.E20-03-0200

Maurichi, A; Miceli, R; Eriksson, H; Newton-Bishop, J; Nsengimana, J; Chan, M; Hayes, AJ; Heelan, K; Adams, D; Patuzzo, R; et al. (2020) Factors Affecting Sentinel Node Metastasis in Thin (T1) Cutaneous Melanomas: Development and External Validation of a Predictive Nomogram. Journal of Clinical Oncology, 38 (14). pp. 1591-1601. ISSN 0732-183X https://doi.org/10.1200/jco.19.01902

Marygold, SJ; Attrill, H; Speretta, E; Warner, K; Magrane, M; Berloco, M; Cotterill, S; McVey, M; Rong, Y; Yamaguchi, M (2020) The DNA polymerases of Drosophila melanogaster. Fly (Austin). pp. 1-13. ISSN 1933-6942 https://doi.org/10.1080/19336934.2019.1710076

Skepper, CK; Armstrong, D; Balibar, CJ; Bauer, D; Bellamacina, C; Benton, BM; Bussiere, D; De Pascale, G; De Vicente, J; Dean, CR; et al. (2020) Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria. J Med Chem, 63 (14). pp. 7773-7816. ISSN 1520-4804 https://doi.org/10.1021/acs.jmedchem.0c00347

Carare, RO; Aldea, R; Agarwal, N; Bacskai, BJ; Bechman, I; Boche, D; Bu, G; Bulters, D; Clemens, A; Counts, SE; et al. (2020) Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy. Alzheimers Dement (Amst), 12 (1). e12053. ISSN 2352-8729 https://doi.org/10.1002/dad2.12053

Moroni, F; Ammirati, E; Hainsworth, AH; Camici, PG (2020) Association of white matter hyperintensities and cardiovascular disease. Circulation-Cardiovascular Imaging, 13 (8). e010460. ISSN 1941-9651 https://doi.org/10.1161/CIRCIMAGING.120.010460 SGUL Authors: Hainsworth, Atticus Henry

McFall, A; Hietamies, TM; Bernard, A; Aimable, M; Allan, SM; Bath, PM; Brezzo, G; Carare, RO; Carswell, HV; Clarkson, AN; et al. (2020) UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings. J Cereb Blood Flow Metab, 40 (7). pp. 1402-1414. ISSN 1559-7016 https://doi.org/10.1177/0271678X20910552

Kim, Y; Kim, S-H (2020) WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System. Endocrinol Metab (Seoul), 35 (3). pp. 494-506. ISSN 2093-5978 https://doi.org/10.3803/EnM.2020.302

Kim, Y; Lee, J; Seppala, M; Cobourne, MT; Kim, S-H (2020) Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration. Nat Commun, 11 (1). p. 1994. ISSN 2041-1723 https://doi.org/10.1038/s41467-020-15897-3

Coates, C; Kerruth, S; Helassa, N; Török, K (2020) Kinetic Mechanisms of Fast Glutamate Sensing by Fluorescent Protein Probes. Biophys J, 118 (1). pp. 117-127. ISSN 1542-0086 https://doi.org/10.1016/j.bpj.2019.11.006

Strokectomy for malignant middle cerebral artery infarction: experience and meta-analysis of current evidence. Moughal S, Trippier S, Al-Mousa A, Hainsworth AH, Pereira AC, Minhas PS, Shtaya A. (2022) J Neurol.;269(1):149-158. doi: 10.1007/s00415-020-10358-9. Epub 2020 Dec 19. PMID: 33340332

Streetley J, Fonseca A, Turner J, Kiskin N, Knipe L, Rosenthal P, Carter T (2019) Stimulated release of intraluminal vesicles from Weibel-Palade bodies Blood (2019) 133 (25): 2707–2717. https://doi.org/10.1182/blood-2018-09-874552

Dilaver, N; Pellatt, L; Jameson, E; Ogunjimi, M; Bano, G; Homburg, R; D Mason, H; Rice, S (2019) The regulation and signalling of anti-Müllerian hormone in human granulosa cells: relevance to polycystic ovary syndrome. Hum Reprod, 34 (12). pp. 2467-2479. ISSN 1460-2350 https://doi.org/10.1093/humrep/dez214

Boltze, J; Ferrara, F; Hainsworth, AH; Bridges, LR; Zille, M; Lobsien, D; Barthel, H; McLeod, DD; Gräßer, F; Pietsch, S; et al. (2019) Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage. J Cereb Blood Flow Metab, 39 (12). pp. 2521-2535. ISSN 1559-7016 https://doi.org/10.1177/0271678X18802119

Norton, EJ; Bridges, LR; Kenyon, LC; Esiri, MM; Bennett, DC; Hainsworth, AH (2019) Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 78 (11). pp. 1066-1072. ISSN 0022-3069 https://doi.org/10.1093/jnen/nlz088

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