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Dr Catrin Moore

Reader in Global Health and Infectious Diseases
Dr Moore researches the burden of antimicrobial resistance and antibiotic use in the community.

Dr Moore is a Reader in Global Health and Infectious Diseases, funded by the Wellcome Trust and Fleming Fund. She works in a multi-disciplinary team and has an interest in drug-resistant infections, with a particular focus on data and interventions to reduce the burden of antibiotic resistance. Her focus is on antimicrobial resistance (AMR) in the community. She is involved in global and regional dialogues around the increase of AMR and the use of antibiotics globally and how to minimise AMR and the misuse of antibiotics, particularly in low- and middle-income countries.

She is a member of the World Health Organization advisory group on Critically Important Antimicrobials for Human Medicine, is the co-chair for the Impact and Influence committee for the Microbiology Society, and is a mentor for Fleming Fund Fellows based in Eswatini. She is currently co-leading the 'Knocking out AMR' initiative which aims to prioritise solutions to minimise the spread and burden of AMR. 

Dr. Catrin Moore’s research focuses on antimicrobial resistance, which is on the increase globally, and is worse in many low- and middle-income countries (LMICs). Dr. Moore is a microbiologist and was based at the University of Oxford for nearly 25 years working in the Global and Public health arena. Her work has focussed on building capacity in resource poor settings. Previously based in Laos and Cambodia she built the microbiology laboratory services and research provision in local hospitals.

Dr. Moore joined the Big Data Institute in May 2018, where she led the Global Research on AntiMicrobial Resistance (GRAM) project. Partnered with the Institute for Health Metrics and Evaluation (IHME) in Seattle and Tropical Medicine in Oxford, they analysed global data to produce health metrics and geospatial maps on antimicrobial resistance (AMR). The first ground-breaking publication to estimate the global burden of AMR was published in the Lancet in January 2022.

Dr Moore is a member of the World Health Organization Advisory Group on Critically Important Antimicrobials (AG CIA) for Human Medicine, a mentor for Fleming Fund Fellows based in Eswatini, and a co-chair for the Impact and Influence committee for the Microbiology Society.

Now based at St George’s, University of London she works closely with researchers in several LMICs on the Antimicrobial use (AMU) Data to Inform Antibiotic guidance and Local Action (ADILA) project and other projects focussing on the burden of AMR and antibiotic exposure in the community.

She has work beginning in Uganda to examine the burden of AMR in the community and to understand the data that informs the WHO GLASS surveillance system. She is passionate about reducing the burden of AMR in the community through meaningful, simple, and sustainable interventions such as the use of diagnostic tools, training, and communication in LMICs.

Please see my ORCID account: https://orcid.org/0000-0002-8639-9846

Some recent papers from 2023-24:

  • Elias C, Raad M, Rasoanandrasana S, Raherinandrasana AH, Andriananja V, Raberahona M, Moore CE, Randria M, Raskine L, Vanhems P, Babin FX. Implementation of an antibiotic resistance surveillance tool in Madagascar, the TSARA project: a prospective, observational, multicentre, hospital-based study protocol. BMJ Open. 2024 Mar 19;14(3):e078504. doi: 10.1136/bmjopen-2023-078504. PMID: 38508637; PMCID: PMC10953040.
  • GBD 2021 Risk Factors Collaborators. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024 May 18;403(10440):2162-2203. doi: 10.1016/S0140-6736(24)00933-4. PMID: 38762324.
  • IHME Pathogen Core Group. Global burden associated with 85 pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Infect Dis. 2024 Apr 16:S1473-3099(24)00158-0. doi: 10.1016/S1473-3099(24)00158-0. Epub ahead of print. PMID: 38640940.
  • GBD 2021 Lower Respiratory Infections and Antimicrobial Resistance Collaborators. Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021. Lancet Infect Dis. 2024 Apr 15:S1473-3099(24)00176-2. doi: 10.1016/S1473-3099(24)00176-2. Epub ahead of print. PMID: 38636536.
  • GBD 2021 Tuberculosis Collaborators. Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Infect Dis. 2024 Mar 19:S1473-3099(24)00007-0. doi: 10.1016/S1473-3099(24)00007-0. Epub ahead of print. PMID: 38518787.
  • Dangor Z, Benson N, Berkley JA, Bielicki J, Bijsma MW, Broad J, Buurman ET, Cross A, Duffy EM, Holt KE, Iroh Tam PY, Jit M, Karampatsas K, Katwere M, Kwatra G, Laxminarayan R, Le Doare K, Mboizi R, Micoli F, Moore CE, Nakabembe E, Naylor NR, O'Brien S, Olwagen C, Reddy D, Rodrigues C, Rosen DA, Sadarangani M, Srikantiah P, Tennant SM, Hasso-Agopsowicz M, Madhi SA. Vaccine value profile for Klebsiella pneumoniae. Vaccine. 2024 Mar 18:S0264-410X(24)00248-2. doi: 10.1016/j.vaccine.2024.02.072. Epub ahead of print. PMID: 38503661.
  • Sinto R, Lie KC, Setiati S, Suwarto S, Nelwan EJ, Karyanti MR, Karuniawati A, Djumaryo DH, Prayitno A, Sumariyono S, Sharland M, Moore CE, Hamers RL, Day NPJ, Limmathurotsakul D. Diagnostic and antibiotic use practices among COVID-19 and non-COVID-19 patients in the Indonesian National Referral Hospital. PLoS One. 2024 Mar 7;19(3):e0297405. doi: 10.1371/journal.pone.0297405. PMID: 38452030; PMCID: PMC10919621.
  • GRAM Typhoid Collaborators. Estimating the subnational prevalence of antimicrobial resistant Salmonella enterica serovars Typhi and Paratyphi A infections in 75 endemic countries, 1990-2019: a modelling study. Lancet Glob Health. 2024 Mar;12(3):e406-e418. doi: 10.1016/S2214-109X(23)00585-5.PMID: 38365414; PMCID: PMC10882211.
  • Ul Mustafa Z, Batool A, Ibrar H, Salman M, Khan YH, Mallhi TH, Meyer JC, Godman B, Moore CE. Bacterial co-infections, secondary infections and antimicrobial use among hospitalized COVID-19 patients in the sixth wave in Pakistan: findings and implications. Expert Rev Anti Infect Ther. 2024 Apr;22(4):229-240. doi: 10.1080/14787210.2023.2299387. Epub 2024 Jan 22. PMID: 38146949.
  • Massele A, Rogers AM, Gabriel D, Mayanda A, Magoma S, Cook A, Chigome A, Lorenzetti G, Meyer JC, Moore CE, Godman B, Minzi O. A Narrative Review of Recent Antibiotic Prescribing Practices in Ambulatory Care in Tanzania: Findings and Implications. Medicina (Kaunas). 2023 Dec 18;59(12):2195. doi: 10.3390/medicina59122195. PMID: 38138298; PMCID: PMC10745081.
  • Antimicrobial Resistance Collaborators. The burden of bacterial antimicrobial resistance in the WHO African region in 2019: a cross-country systematic analysis. Lancet Glob Health. 2024 Feb;12(2):e201-e216. doi: 10.1016/S2214-109X(23)00539-9. Epub 2023 Dec 19. PMID: 38134946; PMCID: PMC10805005.
  • Alam M, Saleem Z, Haseeb A, Qamar MU, Sheikh A, Almarzoky Abuhussain SS, Iqbal MS, Raees F, Chigome A, Cook A, Moore CE, Mustafa ZU, Salman M, Saleh U, Shabbir S, Godman B. Tackling antimicrobial resistance in primary care facilities across Pakistan: Current challenges and implications for the future. J Infect Public Health. 2023 Dec;16 Suppl 1:97-110. doi: 10.1016/j.jiph.2023.10.046. Epub 2023 Nov 2. PMID: 37973496.
  • Sono TM, Yeika E, Cook A, Kalungia A, Opanga SA, Acolatse JEE, Sefah IA, Jelić AG, Campbell S, Lorenzetti G, Ul Mustafa Z, Marković-Peković V, Kurdi A, Anand Paramadhas BD, Rwegerera GM, Amu AA, Alabi ME, Wesangula E, Oluka M, Khuluza F, Chikowe I, Fadare JO, Ogunleye OO, Kibuule D, Hango E, Schellack N, Ramdas N, Massele A, Mudenda S, Hoxha I, Moore CE, Godman B, Meyer JC. Current rates of purchasing of antibiotics without a prescription across sub-Saharan Africa; rationale and potential programmes to reduce inappropriate dispensing and resistance. Expert Rev Anti Infect Ther. 2023 Jul-Dec;21(10):1025-1055. doi: 10.1080/14787210.2023.2259106. Epub 2023 Oct 27. PMID: 37740561.
  • Antimicrobial Resistance Collaborators. The burden of antimicrobial resistance in the Americas in 2019: a cross-country systematic analysis. Lancet Reg Health Am. 2023 Aug 8;25:100561. doi: 10.1016/j.lana.2023.100561. Erratum in: Lancet Reg Health Am. 2023 Nov 10;28:100632. PMID: 37727594; PMCID: PMC10505822.
  • Saleem Z, Haseeb A, Abuhussain SSA, Moore CE, Kamran SH, Qamar MU, Azmat A, Pichierri G, Raees F, Asghar S, Saeed A, Amir A, Hashmi FK, Meyer JC, Sefah IA, Rehman IU, Nadeem MU, Godman B. Antibiotic Susceptibility Surveillance in the Punjab Province of Pakistan: Findings and Implications. Medicina (Kaunas). 2023 Jun 28;59(7):1215. doi: 10.3390/medicina59071215. PMID: 37512028; PMCID: PMC10383515.
  • Kapisi J, Sserwanga A, Kitutu FE, Rutebemberwa E, Awor P, Weber S, Keller T, Kaawa-Mafigiri D, Ekusai-Sebatta D, Horgan P, Dittrich S, Moore CE, Salami O, Olliaro P, Nkeramahame J, Hopkins H. Impact of the Introduction of a Package of Diagnostic Tools, Diagnostic Algorithm, and Training and Communication on Outpatient Acute Fever Case Management at 3 Diverse Sites in Uganda: Results of a Randomized Controlled Trial. Clin Infect Dis. 2023 Jul 25;77(Suppl 2):S156-S170. doi: 10.1093/cid/ciad341.Erratum in: Clin Infect Dis. 2024 Apr 10;78(4):1082-1083. PMID: 37490746; PMCID: PMC10368415.
  • Adjei A, Kukula V, Narh CT, Odopey S, Arthur E, Odonkor G, Mensah MM, Olliaro P, Horgan P, Dittrich S, Moore CE, Salami O, Awini E, Nkeramahame J, Williams J, Baiden R. Impact of Point-of-Care Rapid Diagnostic Tests on Antibiotic Prescription Among Patients Aged <18 Years in Primary Healthcare Settings in 2 Peri-Urban Districts in Ghana: Randomized Controlled Trial Results. Clin Infect Dis. 2023 Jul 25;77(Suppl 2):S145-S155. doi: 10.1093/cid/ciad328.PMID: 37490745; PMCID: PMC10368405.
  • Olliaro P, Nkeramahame J, Salami O, Moore CE, Horgan P, Baiden R, Kukula V, Adjei A, Kapisi J, Hopkins H, Kaawa-Mafigiri D, Ekusai-Sebatta D, Rutebemberwa E, Kitutu FE, Tinto H, Kiemde F, Compaoré A, Valia D, Dittrich S; ADIP study group. Advancing Access to Diagnostic Tools Essential for Universal Health Coverage and Antimicrobial Resistance Prevention: An Overview of Trials in Sub-Saharan Africa. Clin Infect Dis. 2023 Jul 25;77(Suppl 2):S125-S133. doi: 10.1093/cid/ciad326. PMID: 37490744; PMCID: PMC10368407.
  • Olliaro P, Nkeramahame J, Horgan P, Tinto H, Kiemde F, Baiden R, Adjei A, Kapisi J, Hopkins H, Salami O, Moore CE, Dittrich S, Weber S, Ongarello S; ADIP study group. Synthesis and Meta-analysis of 3 Randomized Trials Conducted in Burkina Faso, Ghana, and Uganda Comparing the Effects of Point-of-Care Tests and Diagnostic Algorithms Versus Routine Care on Antibiotic Prescriptions and Clinical Outcomes in Ambulatory Patients <18 Years of Age With Acute Febrile Illness. Clin Infect Dis. 2023 Jul 25;77(Suppl 2):S199-S205. doi: 10.1093/cid/ciad324. PMID: 37490743; PMCID: PMC10368413.
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