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Overview

Dr Irina Chis Ster

Senior Lecturer in Biostatistics
I am a biostatistician with extensive experience in study design and analyses of complex data.
Infection and Immunity Research Institute
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Overview

I provide tailored statistical consultancy on best practices for study design, as well as the subsequent analyses, inference interpretation and publications. My fields of expertise range from clinical trials to epidemiological and biological studies; areas in which I provide statistical advice to a number of faculty members at St George's, University of London and St George's Hospital.  Part of my responsibilities and contributions consist of providing regular guidance to clinical trainees and researchers, through the statistical design and data needed to answer the questions which build their fellowship applications.

Whilst providing direct dissertation supervision to final year BSc, MSc and MRes students interested in learning data analyses processes, my support often extends to my colleagues' students in terms of statistical plans and analyses.

I can be contacted by email for statistical advice - preferably at the very incipient stage of a new project. Please feel free to read my consultancy questions (Word) to help prepare you for our first meeting, including points of discussion and items for consideration.

ORCID

I joined St George’s in June 2013 as tenure track after holding research positions in biostatistics with Imperial College London and University College London. I hold a PhD in Pure Mathematics and an MSc in Medical Statistics (London School of Hygiene and Tropical Medicine).

My research interests and experiences span a variety of observational, epidemiological and clinical data of different complexities, including those featuring spatio-temporal components or hierarchical structure. The latter may arise from patients’ longitudinal observations, individuals within a spatial, administrative or household unit, multiple hospital episodes or clustered survey design. I have extensive experience in using a variety of statistical packages including Stata, OpenBUGS, R, SPSS, SAS as well as programming in C/C++.

My previous work involved developing computationally intensive methodologies for statistical inference in both Bayesian and classical frequentist context. 

I also hold an honorary faculty position with Universidad Internacional del Ecuador, Quito (https://www.uide.edu.ec/) where I teach short postgraduate classes and tutorials in statistical epidemiology as well as participating in developing statistical strategies for future cooperative international projects.   

I have been invited and accepted to be a member of the Statistical Board for the Journal of Critical Care https://www.journals.elsevier.com/journal-of-critical-care/editorial-board.

An important component of my past and current research is my work on deriving infectious diseases prevalence from serological data, particularly for infections which result in life-long immunity. Using dengue and chikungunya serological assays collected in a province in Ecuador during recent outbreaks in South America, I have recently developed a method addressing infectious diseases prevalence inference for two simultaneous infections which share similar clinical manifestations and modes of transmission. 

I lead all the statistical aspects as co-investigator of a Latin America asthma grant (led by Phil Cooper) from design and sample size calculations to planning the analyses. The resulting data would provide an excellent opportunity to formalize a statistical framework for methodologies which address recurrent events in a variety of respiratory conditions.

I am the statistical lead and co-investigator for a trial funded by AstraZeneca held in patients with heart failure conducted by a team of clinicians and scientists at St George's University and Hospital Trust (principal investigator - Dr Debasish Banerjee).

Together with a couple of colleagues from the II&I and NHS Trust, I also investigate the extent to which epidemiological data alone can provide evidence for associations between the length of antimicrobial therapy and emerging resistance to aminoglycosides in neonates based on the last 12 years of routinely hospital collected data.

Furthermore, I am involved in a series of cardio-vascular projects where I  conduct detailed analyses aiming at understanding the burden of various post-mortem diagnoses and other characteristics related to Sudden Death populations - both general and that of professional athletes.

Original scientific research

Papers as first/last/sole author

· Parmar, Simran; Lopez, Tony; Shah, Ronak; Murphy, Daniel; Warrens, Hilary; Khairallah, Marwa; Anderson, Lisa; Rosano, Guiseppe; Chis Ster, Delizia Irina; Banerjee, Debasish, Risk of hospital admissions and death in patients with heart failure and chronic kidney disease: findings from a novel multidisciplinary clinic, CardioRenal Medicine, in press

· Olivia Bird, Eva P. Galiza, David Neil Baxter, Marta Boffito, Duncan Browne, Fiona Burns, David R. Chadwick, Rebecca Clark, Catherine A. Cosgrove, James Galloway, Anna L. Goodman, Amardeep Heer, Andrew Higham, Shalini Iyengar, Christopher Jeanes, Philip A. Kalra, Christina Kyriakidou, Judy M. Bradley, Chigomezgo Munthali, Angela M. Minassian, Fiona McGill, Patrick Moore, Imrozia Munsoor, Helen Nicholls, Orod Osanlou, Jonathan Packham, Carol H. Pretswell, Alberto San Francisco Ramos, Dinesh Saralaya, Ray P. Sheridan, Richard Smith, Roy L. Soiza, Pauline A. Swift, Emma C. Thomson, Jeremy Turner, Marianne Elizabeth Viljoen, Paul T. Heath,* and Irina Chis Ster*, THE PREDICTIVE ROLE OF SYMPTOMS IN COVID-19 DIAGNOSTIC MODELS – A LONGITUDINAL INSIGHT, Epidemiology and Infection (http://dx.doi.org/10.1017/s0950268824000037)

· Aruni Ratnayake; Alexander Sarnowski; Fiona Sinclair; Nicholas Annear; Professor Debasish Banerjee; Irina Chis Ster, The dynamics and outcomes of AKI progression during the COVID-19 pandemic, Nephrology (DOI: 10.1111/nep.14297)

· Monsermin Gualan*, Irina Chis Ster*, Tatiana Veloz, Emily Granadillo, Luz M. Llangari-Arizo, Alejandro Rodriguez, Julia A. Critchley, Peter Whincup, Miguel Martin, Natalia Romero-Sandoval, Philip J. Cooper, Cardiometabolic diseases and associated risk factors in transitional rural communities in tropical coastal Ecuador (DOI: 10.1371/journal.pone.0307403)

· Chis Ster I, Rodriguez A, Romero NC, Lopez A, Chico M, Montgomery J, Cooper P. Age-dependent seroprevalence of dengue and chikungunya: inference from a cross-sectional analysis in Esmeraldas Province in coastal Ecuador. BMJ Open 10(10):e040735 16 (2020)

· Kular D, Chis Ster I**, Sarnowski A, Lioudaki E, Braide-Azikiwe DCB, Ford ML, Makanjuola D, Rankin A, Cairns H, Popoola J, et al. The characteristics, dynamics and risk of death in COVID-19 positive dialysis patients in London, UK, Kidney360 1(11):1226-1243 (2020)

· Chis Ster I**, Niaz HF, Chico ME, Oviedo Y, Vaca M, Cooper PJ, The epidemiology of soil-transmitted helminth infections in children up to 8 years of age: Findings from an Ecuadorian birth cohort, PLoS Negl Trop Dis 15(11):e0009972 (2021)

· Chis Ster I., Inference for serological surveys investigating past exposures to infections resulting in long-lasting immunity - an approach using finite mixture models with concomitant information JOURNAL OF APPLIED STATISTICS 39(11):2523-2542 2012 (Journal article)

· Chis Ster I., Dodd PJ, Ferguson NM. Within-farm transmission dynamics of foot and mouth disease as revealed by the 2001 epidemic in Great Britain. Epidemics 4(3):158-169 Aug 2012 (Journal article)

· Chis Ster I., Singh BK, Ferguson NM. Epidemiological inference for partially observed epidemics: the example of the 2001 foot and mouth epidemic in Great Britain. Epidemics 1(1):21-34 Mar 2009 (Journal article)

· Truscott J, Garske T, Chis-Ster I., Guitian J, Pfeiffer D, Snow L, Wilesmith J, Ferguson NM, Ghani AC. Control of a highly pathogenic H5N1 avian influenza outbreak in the GB poultry flock. Proc Biol Sci 274(1623):2287-2295 22 Sep 2007 (Journal article)

· Chis Ster I., Ferguson NM. Transmission parameters of the 2001 foot and mouth epidemic in Great Britain. PLoS One 2(6):e502 06 Jun 2007 (Journal article)

 

Publications part of my PhD dissertation

· Chis-Ster I., Existence of monotone solutions for semilinear differential inclusions NODEA-NONLINEAR DIFFERENTIAL EQUATIONS AND APPLICATIONS 6(1):63-78 Feb 1999 (Journal article) View record in Web of Science

· Chis Ster I. EXISTENCE OF MONOTONE SOLUTIONS FOR NONLINEAR PERTURBED DIFFERENTIAL INCLUSIONS Rev.R.Ac ad. Cieñe. Exact. F is.Nat. (Esp) Vol. 93, N." 2, pp 189-194, 1999 Matemáticas (Journal article)

· Chis Ster I. MONOTONE SOLUTIONS FOR SINGLE VALUED PERTURBED NONLINEAR EVOLUTION EQUATIONS Communications in Applied Analysis 5 (2001), no. 3,295-306 (Journal article)

· Chis Ster I,. EXISTENCE OF MONOTONE SOLUTIONS FOR A PARABOLIC PROBLEM ANALELE STIINTIFICE ALE UNIVERSITATII ”AL.I.CUZA” IASI ˘ Tomul XLIII, s.I.a, Matematic˘a, 1997, f2 (Journal article)

 

Papers in collaboration as sole statistician

· Leon-Rojas, Jose E.; Arias-Erazo, Fernanda;Jiménez-Arias, Patricia;Recalde-Navarrete, Ricardo; Guevara, Angel; Coloma, Josefina; Martin, Miguel; Irina Chis Ster, Philip Cooper, Romero-Sandoval, Natalia; and the Seroprevalence ECU-Group, COVID-19 IgG seropositivity and its determinants in occupational groups of varying infection risks in two Andean cities of Ecuador before mass vaccination, (DOI: 10.1371/journal.pone.0309466)

· Molina-Cando, María José; Chis Ster, Delizia Irina; Escandón, Samuel; Sanchez, René-Vinicio; Rodriguez, Alejandro; Chico, Martha E.; Vaca, Maritza; Owen, Christopher G.; Van Dyck, Delfien; Cooper, Philip J.; Ochoa-Aviles, Angelica; Attainment of World Health Organization physical activity recommendations by Ecuadorian children: analysis of social and anthropometrics factors in two distinct populations; PLOS ONE, in press

· Jose E. Leon-Rojas, Tatiana Veloz, Jair Teran, Monica Perez3, Fernanda Arias-Erazo, Lizet Villacis, Jorge Velez6, Ricardo Recalde, Patricia Jiménez, Miguel Martin, Irina Chis Ster, Philip Cooper, Natalia Romero, The dynamics and determinants of specific systemic and mucosal antibody responses to SARS-CoV-2 in three adult cohorts in the Ecuadorian Andes: a study protocol (DOI: 10.12688/f1000research.126577.2)

· Helena Benes Matos da Silva1,2, Rita de Cássia Ribeiro-Silva1,2, Juliana Freitas de Mello e Silva2, Irina Chis Ster3, Maria Yury Ichihara2, Poliana Rebouças de Magalhães2, Emanuelle Goes2, Andrea Ferreira2, Júlia Pescarini4, Rosemeire Fiaccone5, Enny S. Paixão4, Maurício L. Barreto2 Ethno-racial disparities in childhood growth trajectories in Brazil: a longitudinal nationwide study of four million children, BMC pediatrics, (DOI: 10.1186/s12887-024-04550-3)

· Tannya Sandoval-Ramırez, Victor Seco-Hidalgo, Evelyn Calderon-Espinosa, Diana Garcia-Ramon1, Andrea Lopez, Manuel Calvopiña , Irene Guadalupe, Martha Chico5 , Rojelio Mejia, Irina Chis Ster, Philip J. Cooper, Epidemiology of giardiasis and assemblages A and B and effects on diarrhea and growth trajectories during the first 8 years of life: Analysis of a birth cohort in a rural district in tropical Ecuador, PLOS NEGLECTED TROPICAL DISEASES, 2023

· Dimitra Nikoletou; Irina Chis Ster; Carmen Y Lech; Iain S MacNaughton; Felix Chua; Raminder Aul; Paul W Jones, Comparison of high-intensity interval training versus moderate-intensity continuous training in pulmonary rehabilitation for interstitial lung disease: a randomised controlled pilot feasibility trial, BMJ OPEN, 2023

· Joseph Westaby; Chiara Dalle-Carbonare; Irina Chis Ster; Mary N. Sheppard, Obesity Cardiomyopathy in Sudden Cardiac Death: A Distinct Entity? A Comparative Study, JACC: ADVANCES, 2023

· Diana Morillo, Santiago Mena-Bucheli, Angélica Ochoa, Martha E Chico, Claudia Rodas, Augusto Maldonado, Karen Arteaga, Jessica Alchundia, Karla Solorzano, Alejandro Rodriguez, Camila Figueiredo, Cristina Ardura-Garcia, Max Bachmann , Michael Richard Perkin, Irina Chis Ster, Alvaro Cruz, Natalia Cristina Romero, Philip Cooper; Prospective study of factors associated with asthma attack recurrence (ATTACK) in children from three Ecuadorian cities during COVID-19: a study protocol, BMJ Open 2022

· Babu, Aswin; Meng, Zhaoyi; Eden, Nadia; Lamb, Daniel; Nouza, Jan, Bhatia, Raghav; Chis Ster, Irina; Bennett, Jonathan; Voon, Victor, Evaluating the role of transthoracic echocardiography in hospitalised patients with COVID-19 infection, BMJ Open Heart 2022

· JD Westaby, C Miles, I Chis Ster, STE Cooper, TF Antonios, D Meijles, ER Behr, MN Sheppard. (2022). Characterisation of hypertensive heart disease: pathological insights from a sudden cardiac death cohort to inform clinical practice. J Hum Hypertens, 36(3), 246-253. doi:10.1038/s41371-021-00507-6

· Belinda Gray, Alban-Elouen Baruteau, Albert A Antolin, Alan Pittman, Giselle Sarganas, Mariam Molokhia, Marieke T Blom, Rachel Bastiaenen, Abdenasser Bardai, Silvia G Priori, Carlo Napolitano, Peter E Weeke, Saad A Shakir, Wilhelm Haverkamp, Jordi Mestres, Bo Winkel, Adam A Witney, Irina Chis-Ster, Ajanthah Sangaralingam, A John Camm, Jacob Tfelt-Hansen, Dan M Roden, Hanno L Tan, Edeltraut Garbe, Miriam Sturkenboom, Elijah R Behr (2022). Rare Variation in Drug Metabolism and Long QT Genes and the Genetic Susceptibility to Acquired Long QT Syndrome. Circ Genom Precis Med, 15(1), e003391. doi:10.1161/CIRCGEN.121.003391

· MURPHY, D*1 , Warrens, H2 , Nihil, C2 , Appelbaum, E3 , Kaski, JC1,4 , Chis Ster, I5 , Banerjee, D, MEASURING LEFT VENTRICULAR MASS AND EJECTION FRACTION BY CARDIAC MRI AND ECHOCARDIOGRAPHY IN PATIENTS WITH CKD (report), Kidney International Reports https://doi.org/10.1016/j.ekir.2022.01.283

· Miles C, Asimaki A, Chis Ster I, Papadakis M, Gray B, Westaby J, Finocchiaro G, Bueno-Beti C, Ensam B, Basu J, Parry-Williams G, MacLachlan H, Edwards KA, Johnson D, Tome M, Sharma S, Sheppard MN, Behr ER, Biventricular Myocardial Fibrosis and Sudden Death in Patients With Brugada Syndrome, J Am Coll Cardiol 78(15):1511-1521 12 Oct 2021

· Murphy D, Chis Ster Irina, Kaski JC, Anderson L, Banerjee D, The LIFT trial: study protocol for a double-blind, randomised, placebo-controlled trial of K +-binder Lokelma for maximisation of RAAS inhibition in CKD patients with heart failure, BMC Nephrology, 2021; 22: 254.

· Philip John Cooper, Irina Chis Ster, Martha E Chico, Maritza Vaca, Mauricio L. Barreto and David P Strachan, Patterns of allergic sensitization and determinants of emergence of sensitization in the rural tropics early in the life course: findings of an Ecuadorian birth cohort, Frontiers in Allergy, 2:687073 05

· Calvert A, Vandrevala T, Parsons R, Barber V, Book A, Book G, Carrington D, Greening V, Griffiths P, Hake D, Khalil A, Luck S, Montague A, Star C, Irina Chis Ster , Wood S, Heath PT, Jones CE; Changing knowledge, attitudes and behaviours towards cytomegalovirus in pregnancy through film-based antenatal education: a feasibility randomised controlled trial of a digital educational intervention, BMC Pregnancy Childbirth 21(1):565 18 Aug 2021

· Angélica M. OCHOA-AVILÉS, Cristina OCHOA-AVILÉS, Diana A. MORILLO-ARGUDO, María José MOLINA-CANDO, Claudia R. RODAS-ESPINOZA, Irina Chis Ster, Manolo P. MAESTRE CALDERÓN, Augusto MALDONADO G, Karen ARTEAGA VACA, Alejandro RODRIGUEZ, Alvaro A. CRUZ, Natalia ROMERO-SANDOVAL, Philip J. COOPER, Impact of COVID-19 pandemic on asthma symptoms and management: a prospective analysis of asthmatic children in Ecuador, World Allergy Organization Journal, in press

· Philip J. Cooper, Irina Chis Ster, Martha E. Chico, Maritza Vaca, Yisela Oviedo, Augusto Maldonado, Mauricio L. Barreto, Thomas A. E. Platts‐Mills, David P. Strachan, Impact of early life geohelminths on wheeze, asthma and atopy in Ecuadorian children at 8 years, Allergy 76(9):2765-2775 Sep 2021

· J. D. Westaby, C. Miles, I. Chis Ster, S. T. E. Cooper, T. F. Antonios, D. Meijles, E. R. Behr & M. N. Sheppard, Characterisation of hypertensive heart disease: pathological insights from a sudden cardiac death cohort to inform clinical practice JOURNAL OF HUMAN HYPERTENSION

· Oviedo-Vera AY, Chis Ster I, Chico ME, Silva MB, Salazar-Garcés LF, Alcantara-Neves NM, Cooper PJ, A prospective seroepidemiological study of toxocariasis during early childhood in coastal Ecuador: potential for congenital transmission and risk factors for infection., Parasit Vectors 14(1):95 05 Feb 2021

· Phanish M, Chis Ster I, Ghazanfar A, Cole N, Quan V, Hull R, Banerjee D. Systematic review and meta-analysis of COVID-19 and kidney transplant recipients, the South West London Kidney Transplant Network experience. Kidney Int Rep 19 Dec 2020

· Zitouni K, Steyn MRCP, Lyka E, Kelly FJ, Cook P, Chis Ster I, Earle KA. Derepression of glomerular filtration, renal blood flow and antioxidant defence in patients with type 2 diabetes at high-risk of cardiorenal disease, Free Radic Biol Med 161:283-289 Dec 2020

· Nguyen M, Rumjaun S, Lowe-Jones R, Chis Ster I, Rosano G, Anderson L, Banerjee D. Management and outcomes of heart failure patients with CKD: experience from an inter-disciplinary clinic. ESC Heart Fail 7(5):3225-3230 Oct 2020

· D'Silva A, Captur G, Bhuva AN, Jones S, Bastiaenen R, Abdel-Gadir A, Gati S, van Zalen J, Willis J, Malhotra A, Irina Chis Ster Charlotte Manisty AlunD.Hughes Guy Lloyd Rajan Sharma James C. Moon Sanjay Sharma, Recreational marathon running does not cause exercise-induced left ventricular hypertrabeculation. Int J Cardiol 315:67-71 15 Sep 2020

· Miles C, Westaby J, Chis Ster I, Asimaki A, Boardman P, Joshi A, Papadakis M, Sharma S, Behr ER, Sheppard MN. Morphometric characterization of collagen and fat in normal ventricular myocardium. Cardiovasc Pathol 48:107224 Sep 2020

· Alakbarzade V, Huang X, Chis Ster I, McEntagart M, Pereira AC. High on-clopidogrel platelet reactivity in ischaemic stroke or transient ischaemic attack: Systematic review and meta-analysis. J Stroke Cerebrovasc Dis 29(7):104877 Jul 2020

· Banerjee D, Popoola J, Shah S, Chis Ster I, Quan V, Phanish M. COVID-19 infection in kidney transplant recipients Kidney International 97(6):1076-1082 Jun 2020 (Journal article)

· D'Silva, Andrew; Bhuva, Anish N.; van Zalen, Jet; Bastiaenen, Rachel; Abdel-Gadir, Amna; Jones, Siana; Nadarajan, Niromila; Menacho Medina, Katia D.; Ye, Yang; Augusto, Joao; Treibel, Thomas A.; Rosmini, Stefania; Ramlall, Manish; Scully, Paul R.; Torlasco, Camilla; Willis, James; Finocchiaro, Gherardo; Papatheodorou, Efstathios; Dhutia, Harshil; Cole, Della; Chis Ster, Irina; Hughes, Alun D.; Sharma, Rajan; Manisty, Charlotte; Lloyd, Guy; Moon, James C.; Sharma, Sanjay, Cardiovascular Remodeling Experienced by Real-World, Unsupervised, Young Novice Marathon Runners. Front Physiol 11:232 2020 (Journal article) 2019

· Banerjee D, Chitalia N, Chis Ster I, Appelbaum E, Thadhani R, Kaski JC, Goldsmith D. Impact of Vitamin D on Cardiac structure and function in CKD patients with hypovitaminosis D, a randomised controlled trial and meta-analysis. Eur Heart J Cardiovasc Pharmacother 12 Dec 2019

· Ruden S, Rieder A, Chis Ster I, Schwartz T, Mikut R, Hilpert K. Synergy Pattern of Short Cationic Antimicrobial Peptides Against Multidrug-Resistant Pseudomonas aeruginosa. Front Microbiol 10:2740 2019

· Miles C, Finocchiaro G, Papadakis M, Gray B, Westaby J, Ensam B, Basu J, Parry-Williams G, Papatheodorou E, Paterson C, Malhotra A, Robertus JL, Ware JS, Cook SA, Asimaki A, Witney A, Irina Chis Ster, Tome M, Sharma S, Behr ER, Sheppard MN, Sudden Death and Left Ventricular Involvement in Arrhythmogenic Cardiomyopathy. Circulation 139(15):1786-1797 09

· Watson X, Chereshneva M, Odor PM, Chis Ster I, Pan-London Perioperative Audit and Research Network (PLAN), Cecconi M. Adoption of Lung Protective ventilation IN patients undergoing Emergency laparotomy: the ALPINE study. A prospective multicentre observational study. Br J Anaesth 121(4):909-917 Oct 2018 (Journal article)

· Kumar S, Chis Ster I, Pollok R, Muscat I, Planche TD. The Epidemiology of Community Clostridium difficile Infection: A Five-Year Population-Based Study on the Bailiwick of Jersey, Channel Islands. Infect Control Hosp Epidemiol 39(5):603-607 May 2018 (Journal article)

· Dixon JJ, Lane K, Dalton RN, Turner C, MacPhee IAM, Chis Ster I, Philips BJ. Continuous Infusion of Low-Dose Iohexol Measures Changing Glomerular Filtration Rate in Critically Ill Patients. Crit Care Med 46(3):e190-e197 Mar 2018 (Journal article)

· Staines HM, Burrow R, Teo BH-Y, Chis Ster I, Kremsner PG, Krishna S. Clinical implications of Plasmodium resistance to atovaquone/proguanil: a systematic review and meta-analysis. J Antimicrob Chemother 73(3):581-595 01 Mar 2018 (Journal article)

· Arnold A, Cooke GS, Kon OM, Dedicoat M, Lipman M, Loyse A, Chis Ster I, Harrison TS. Adverse Effects and Choice between the Injectable Agents Amikacin and Capreomycin in Multidrug-Resistant Tuberculosis. Antimicrob Agents Chemother 61(9)

· Dhutia H, Malhotra A, Yeo TJ, Chis Ster I, Gabus V, Steriotis A, Dores H, Mellor G, García-Corrales C, Ensam B, et al. Inter-Rater Reliability and Downstream Financial Implications of Electrocardiography Screening in Young Athletes. Circ Cardiovasc Qual Outcomes 10(8):e003306

· Arnold A, Cooke GS, Kon OM, Dedicoat M, Lipman M, Loyse A, Butcher PD, Chis Ster I, Harrison TS. Drug resistant TB: UK multicentre study (DRUMS): Treatment, management and outcomes in London and West Midlands 2008-2014. J Infect 74(3):260-271

· Aya HD, Rhodes A, Chis Ster I, Fletcher N, Grounds RM, Cecconi M. Hemodynamic Effect of Different Doses of Fluids for a Fluid Challenge: A Quasi-Randomized Controlled Study. Crit Care Med 45(2):e161-e168

· Odor PM, Chis Ster I, Wilkinson I, Sage F. Effect of admission fascia iliaca compartment blocks on post-operative abbreviated mental test scores in elderly fractured neck of femur patients: a retrospective cohort study. BMC Anesthesiol 17(1):2

Bustinduy AL, Chis Ster I, Shaw R, Irwin A, Thiagarajan J, Beynon R, Ladhani S, Sharland M, CABIN network. Predictors of fever-related admissions to a paediatric assessment unit, ward and reattendances in a South London emergency department: the CABIN 2 study. Arch Dis Child 102(1):22-28

· Bastiaenen R, Pantazis A, Gonna H, Chis-Ster I, Castelletti S, Batchvarov VN, Domenichini G, Coccolo F, Boriani G, McKenna WJ, et al. The ventricular ectopic QRS interval (VEQSI): Diagnosis of arrhythmogenic right ventricular cardiomyopathy in patients with incomplete disease expression. Heart Rhythm 13(7):1504-1512

· Aya HD, Chis Ster I, Fletcher N, Grounds RM, Rhodes A, Cecconi M. Pharmacodynamic Analysis of a Fluid Challenge. Crit Care Med 44(5):880-891

· Odor PM, Bampoe S, Hayward J, Chis Ster I, Evans E. Intrapartum epidural fixation methods: a randomised controlled trial of three different epidural catheter securement devices. Anaesthesia 71(3):298-305

· Ames PRJ, Merashli M, Chis Ster I, D'Andrea G, Iannaccone L, Marottoli V, Margaglione M, Brancaccio V. Survival in primary antiphospholipid syndrome. A single-centre cohort study. Thromb Haemost 115(6):1200-1208 02 Jun 2016

· Merashli M, Chis Ster I, Ames PRJ. Subclinical atherosclerosis in Behcet's disease: A systematic review and meta-analysis. Semin Arthritis Rheum 45(4):502-510 Feb 2016

· Benjamin P, Zeestraten E, Lambert C, Chis Ster I, Williams OA, Lawrence AJ, Patel B, MacKinnon AD, Barrick TR, Markus HS. Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials. J Cereb Blood Flow Metab 36(1):228-240 Jan 2016

· Merashli M, Chis Ster I, Ames PRJ. ATHEROSCLEROSIS IN BEHCET DISEASE: A SYSTEMATIC REVIEW & METANALYSIS ANNALS OF THE RHEUMATIC DISEASES 74:403-403 Jun 2015 (Journal article) View record in Web of Science

· Gauthaman N, Henry D, Chis Ster I, Khunda A, Doumouchtsis SK. Kielland's forceps: does it increase the risk of anal sphincter injuries? An observational study. Int Urogynecol J 26(10):1525-1532 Oct 2015 (Journal article)

· Wazir U, Sanders AJ, Wazir AMA, Ye L, Jiang WG, Chis Ster I, Sharma AK, Mokbel K. Effects of the knockdown of death-associated protein 3 expression on cell adhesion, growth and migration in breast cancer cells. Oncol Rep 33(5):2575-2582 May 2015 (Journal article)

· Alassar A, Soppa G, Edsell M, Rich P, Roy D, Chis Ster I, Joyce R, Valencia O, Barrick T, Howe F, et al. Incidence and mechanisms of cerebral ischemia after transcatheter aortic valve implantation compared with surgical aortic valve replacement. Ann Thorac Surg 99(3):802-808 Mar 2015 (Journal article)

· Krishna S, Ganapathi S, Chis Ster I, Saeed MEM, Cowan M, Finlayson C, Kovacsevics H, Jansen H, Kremsner PG, Efferth T, et al. A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer. EBioMedicine 2(1):82-90 Jan 2015

· Wazir U, Sanders AJ, Wazir A, Baig RM, Jiang WG, Chis Ster I, Sharma AK, Mokbel K. Effect of the knockdown of death-associated protein 1 expression on cell adhesion, growth and migration in breast cancer cells. Oncol Rep 33(3):1450-1458 Mar 2015 (Journal article)

· Gauthaman N, Henry D, Chis-Ster I, Khunda A, Doumouchtsis SK. KIELLAND'S FORCEPS. DOES IT INCREASE THE RISK OF OASIS? NEUROUROLOGY AND URODYNAMICS. 33: 880-881. Aug 2014 (Conference) View record in Web of Science

· Edgeworth JD, Chis Ster I., Wyncoll D, Shankar-Hari M, McKenzie CA. Long-term adherence to a 5 day antibiotic course guideline for treatment of intensive care unit (ICU)-associated Gram-negative infections. J Antimicrob Chemother 69(6):1688-1694 Jun 2014 (Journal article)

Please visit my ORCID

Successful grants include:

  • Adoption of Lung Protective ventilation in patients undergoing emergency laparotomy (ALPINE).
    Funder:  NIAA-AAGBI (National Institute of Academic Anaesthesia)
  • Reducing Acquisition of CMV through antenatal Education: A feasibility study to assess an educational intervention to prevent cytomegalovirus infection in pregnancy (RACE FIT). Funder: NIHR with Dr Chrissie Jones and Prof Paul Heath)
  • Novel Methods for Risk Assessment of Patients with Brugada Syndrome: The London and Belfast Brugada Collaboration (LBBC)  (Funder: British Heart Foundation grant with Elijah Behr)
  • Asthma attacks in Latin America - 2 million grant with (led by Phil Cooper) and International consortium which include experts from Ecuador and Brazil and UK. Funder: NIHR
  • LiFT  - Lokelma for maximisation of RAAS inhibition in CKD patients with Heart Failure; a randomized double blind placebo controlled Trial - 295,000£ Funder: AstraZeneca. The funder bears no responsibilities in conducting, implementing and disseminating the results of the trial which is held at St George's (Clinical lead and expertise -  Prof Debasish Banerjee).
  • NIHR Global Health Research Unit on Social and Environmental Determinants of Health Inequalities (~7 million) - international cooperation between UK-Brazil-Ecuador (Lead applicant Prof Alastair Leyland-MRC/CSO Social and Public Health Sciences Unit and Prof Phil Cooper co-lead at St. George's University of London)
  • Statistical lead for Prevention of Admissions for CKD Patients (60k). Funder: South West London Integrated Care system. (Clinical lead and expertise - Prof Debasish Banerjee)

PhD students :

  • Batul Rojeab Bravo (NIHR funded) - primary supervisor - with Phil Cooper and Ruth Dundas (University of Glasgow)
  • Diego Oswaldo Andrade Ortiz (NIHR funded) - secondary supervisor -  with Ruth Dundas and Jonathan Olsen (University of Glasgow) 
  • Mahrukh Ali - secondary supervisor -  with Debasish Banerjee

 

MD students:

  • Ella Tumelty - secondary supervisor -  with Debasish Banerjee

 

Main cooperators on various projects include but not limited to:

St George’s University

Professor Phil Cooper

Professor Paul Heath

Professor Elijah Behr

St George’s NHS Hospital Trust

Professor Debasish Banerjee

Dr Ken Earle

Dr Justin Richards

UK

Professor Max Bachmann - University of East Anglia

Professor Ruth Dundas - 

Dr Jonathan Olsen

Internationally

Dr Natalia Cristina Romero Sandoval

Dr Alejandro Rodriguez

Dr Diana Garcia

Dr Victor Seco Hidalgo

I deliver a range of lectures in statistics applied to epidemiology and clinical data and lead a planned postgraduate module in Population Health Data Research - part of MSc Translational Medicine degree. Topics include:

Undergraduate lectures include

  • Learning from the data in biomedical research
  • Basic statistics with R (elementary tests and regression techniques for various types of outcomes)
  • Exploratory data  techniques (principal component analysis, cluster analysis)

Postgraduate topics (past and current) include

  • Longitudinal data analyses
  • Basic concepts in artificial intelligence  - supervised and unsupervised data learning
  • Bayesian statistical analyses using OpenBUGS, R and Stata.
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