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Dr Louise Hill joined St George’s in 2015 and is a Clinical Lecturer in Paediatric Infectious Diseases.
Louise’s research interests are focused on neonatal sepsis and strategic antibiotic trials. She co-ordinated the EC FP7 funded NeoVanc trial which compared a neonatal optimised vancomycin regimen to a standard regimen and led on the microbiological sub-analyses. Her PhD focused on the optimisation of vancomycin in treating neonatal Gram-positive sepsis and she was an invited member of the UKHSA Staphylococcus capitis Incident Management Team as a result of this work. She is the co-Chief Investigator for the NeoVanc Long-term Follow-up study which will assess hearing outcomes in NeoVanc participants.
Louise is involved in several global neonatal sepsis prevention and treatment randomised controlled trials, including NeoVTAMR and NeoSep1. NeoSep1, sponsored by the Global Antibiotic Research and Development Partnership, aims to recruit 3000 neonates globally. Louise has led on the extensive feasibility process of potential sites across five WHO regions and has undertaken work to modify neonatal adverse event grading tools to the LMIC setting, adapting them to facilitate grading regardless of the availability of resources, expertise or equipment. Louise was recently invited to speak at a WHO Paediatric Drug Optimization for antibiotics meeting presenting on the challenges and opportunities in conducting neonatal antibiotic trials.
In addition to her research, Louise is co-Lead for the Clinical Trials module as part of the MSc in Applied Biomedical Science.
Louise’s research interests include improving outcomes in neonatal sepsis, particularly in low- and middle- income settings, and strategic antibiotic trials.
Louise has a particular interest in coagulase negative staphylococci (CoNS) which was the focus of her PhD. Her research has included investigating outcomes in septic neonates by CoNS species, as well as characterising resistance patterns by species including evaluating vancomycin heteroresistance in invasive isolates.
Research Group
Centre for Neonatal and Paediatric Infection
Research Team
Professor Mike Sharland
Professor Paul Heath
Professor Jodi Lindsay
Dr Julia Bielicki
Dr Tim Planche
Dr Irene Monahan
Dr Tatiana Munera Huertas
Miss Caroline Albrecht
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